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AI Biotech/Diagnostics: Cardio

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Application US20190333642


Published 2019-10-31

Generating Approximations Of Cardiograms From Different Source Configurations

Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.



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2 Independent Claims

  • 1. A method performed by a computing device for generating derived electromagnetic data for an electromagnetic source within a body, the method comprising: accessing modeled electromagnetic output for a first model of the electromagnetic source over time, the first model based on a first source configuration specifying a first anatomy, the modeled electromagnetic output generated using a computational model of the electromagnetic source, the computational model for generating modeled electromagnetic output of the electromagnetic source over time based on a model based on a source configuration; accessing a second model of the electromagnetic source based on a second source configuration specifying a second anatomy; and generating derived electromagnetic data for the second model of the electromagnetic source based on the modeled electromagnetic output for the first model of the electromagnetic source, factoring in differences between the first anatomy and the second anatomy.

  • 7. A computing system for generating a cardiogram for a heart, the computing system comprising: one or more computer-readable storage mediums storing: a modeled electromagnetic output for a first arrhythmia model of the heart over time, the first arrhythmia model based on a first anatomy, the modeled electromagnetic output generated using a computational model of a heart, the computational model for generating modeled electromagnetic output of the heart over time based on an arrhythmia model; and a second arrhythmia model based on a second anatomy; and computer-executable instructions for controlling the computing system to generate a cardiogram for the second arrhythmia model based on the modeled electromagnetic output for the first arrhythmia model, factoring in differences between the first anatomy and the second anatomy; and one or more processors for executing the computer-executable instructions stored in the one or more computer-readable storage mediums.