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Application US20180258439
Published 2018-09-13
Cannabis Plants Having Modified Expression Of Thca Synthase
The invention relates to novel genetically modified plants and methods or materials, such as polynucleotides, expression cassettes, or vectors for producing the same. Moreover, the invention relates to altering the content of cannabinoids in plants and to medical compositions derived from such plants. In particular embodiments, the present invention relates to cannabis plants having modified expression of tetrahydrocannabinolic acid (THCA) synthase and methods of modifying the amount of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in cannabis by modifying expression of THCA synthase.
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- 1. A method for altering a content of one or more cannabinoids in a cannabis plant, the method comprising down-regulating activity of tetrahydrocannabinolic acid (THCA) synthase in the cannabis plant.
- 13. A seed of the transgenic plant of claim wherein the seed comprises the, 12 selected DNA
- 14. A cannabis plant with reduced delta-9-tetrahydrocannabinol (THC) content, increased cannabidiol (CBD) content, or decreased THC and increased CBD content comprising decreased expression of tetrahydrocannabinolic acid (THCA) synthase.
