Abstract: |
An immunogenic CD40-targeted trimeric MERS-CoV S1 fusion polypeptide as well as a corresponding polynucleotide encoding it and its use for safely inducing immune responses directed against MERS-CoV without inducing vaccine associated respiratory pathologies associated with non-targeted vaccines. |
Inventor: |
Hashem, Anwar M. (Jeddah, SA) |
Applicant: |
King Abdulaziz University (Jeddah, SA) |
Face Assignee: |
King Abdulaziz University (Jeddah, SA) |
Filed: |
2020-08-06 |
Issued: |
2020-10-20 |
Claims: |
6 |
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US10806784
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1. A polypeptide rAd5-S1/F/CD40L which comprises the amino acid sequence of SEQ ID NO: 12.
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